A definition:

grief
  /grif/ Show Spelled Pronunciation [greef] Show IPA

–noun
1. keen mental suffering or distress over affliction or loss; sharp sorrow; painful regret.
2. a cause or occasion of keen distress or sorrow.
—Idioms
3. come to grief, to suffer disappointment, misfortune, or other trouble; fail: Their marriage came to grief after only two years.
4. good grief, (used as an exclamation of dismay, surprise, or relief): Good grief, it's started to rain again!